I think this is first time we hear about this. As @Peacekeeper said, try to change the boot settings.
Alternatively I would change Legacy USB devices setting too.
Nitrokey HSM does not have any other interfaces, than the CCID / smart card access, so BIOS should not really get stuck on it.
Even if I put the Nitrokey in, when I am in the BIOS config menu, the BIOS freezes. So it seems, as soon as the USB device is recognizes and probed the system freezes… - until the OS (Here Linux) is booted…
I am sorry, but I do not have any other ideas.
Here I’ve found a similar topic with Nitrokey Pro: UEFI boot slow with Nitrokey Pro plugged in.
Regarding workaround for now, I would use another machine to access the device over the network, e.g. with a Raspberry PI.
Appreciate! Let me know if I should test some more things. Oh by the way: The red LED lights once before the BIOS freezes, as usual. Not sure if this could give you an indication that a “probe” of the device by the BIOS has already happened or not or is just a sign that it got proper power.